IFIX rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES15528-50, ES15528-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human IFIX AA range: 338-388

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 149628

Human SWISS Prot NO: Q6K0P9

Subcellular Location: [Isoform 1]: Nucleus, nucleoplasm.; [Isoform 3]: Nucleus, nucleoplasm.; [Isoform 5]: Nucleus. Nucleus speckle.

Research Use Only