Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs).

Product information

CAS Number: 1116085-99-4

Molecular Weight: 640.81

Formula: C41H44N4O3

Chemical Name: (2S)-2-[(2S)-2-amino-N-[4-(hydroxymethyl)phenyl]-3-phenylpropanamido]-6-[(triphenylmethyl)amino]hexanamide

Smiles: NC(=O)[C@H](CCCCNC(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)N(C(=O)[C@@H](N)CC1C=CC=CC=1)C1C=CC(CO)=CC=1

InChiKey: SWCZCKQSLIJFDP-UWXQCODUSA-N

InChi: InChI=1S/C41H44N4O3/c42-37(29-31-15-5-1-6-16-31)40(48)45(36-26-24-32(30-46)25-27-36)38(39(43)47)23-13-14-28-44-41(33-17-7-2-8-18-33,34-19-9-3-10-20-34)35-21-11-4-12-22-35/h1-12,15-22,24-27,37-38,44,46H,13-14,23,28-30,42H2,(H2,43,47)/t37-,38-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.