ZFYVE19 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3729-50, ES3729-100

Citations, Manuals and MSDS Available upon request.

Background: disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t (11; 15) (q23; q14) with MLL/HRX., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 FYVE-type zinc finger., tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.,

Alternate Name: ZFYVE19; MPFYVE; Zinc finger FYVE domain-containing protein 19; MLL partner containing FYVE domain

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human ZFYVE19. AA range:311-360

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 50kD

Human Gene ID: 84936

Human SWISS Prot NO: Q96K21

Subcellular Location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody, Midbody ring. Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis.

Research Use Only