Annatto-E™ 300 contains 300 mg per softgel of delta/gamma tocotrienols. Commercial vitamin E supplements are typically rich in tocopherols and low or absent in tocotrienols; however, tocotrienol fractions have unique beneficial effects across a variety of tissues that make them desirable for supporting many aspects of health. Research indicates that tocopherols — especially alpha-tocopherol — may interfere with key clinical effects of tocotrienols, so it may be best to take tocotrienols alone, without tocopherols.