PARP1 (7A1) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3202-50, MB3202-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P09874

Host: Mouse

Reactivity: Human, Mouse, Rat, Chicken

Applications: WB,

All Applications: WB: 1/500-1/1000

Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 113 kDa; Observed MW: 116 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PARP in K562, Ramos, Jurkat lysates using PARP antibody., Western blot analysis of PARP1 in CHO-K1, rat brain, C6, 3T3, Hela lysates using PARP antibody.

Alternative Name: PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

Immunogen: Synthetic Peptide of PARP

Conjugate: Unconjugated

Modification: Unmodified