MQAE is a fluorescent indicator that is quenched via collision with chloride, and is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells.

Product information

CAS Number: 162558-52-3

Molecular Weight: 326.19

Formula: C14H16BrNO3

Chemical Name: 1-(2-ethoxy-2-oxoethyl)-6-methoxyquinolin-1-ium bromide

Smiles: [Br-].COC1=CC2=CC=C[N+](CC(=O)OCC)=C2C=C1

InChiKey: DSLLHVISNOIYHR-UHFFFAOYSA-M

InChi: InChI=1S/C14H16NO3.BrH/c1-3-18-14(16)10-15-8-4-5-11-9-12(17-2)6-7-13(11)15;/h4-9H,3,10H2,1-2H3;1H/q+1;/p-1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 35 mg/mL (107.30 mM). H2O : 100 mg/mL (306.57 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Bath-applied to acute brain slices, MQAE provides high-quality labeling of neuronal cells and their processes. MQAE fluorescence is adequate and comparable method for measuring cAMP-dependent chloride transport in individual cells. MQAE can be used to measure intracellular chloride concentration in primary cultures of rat aortic smooth muscle cells (VSMC).

Products are for research use only. Not for human use.